White Matter Disease Correlates with Lexical Retrieval Deficits in Primary Progressive Aphasia
نویسندگان
چکیده
منابع مشابه
White Matter Disease Correlates with Lexical Retrieval Deficits in Primary Progressive Aphasia
OBJECTIVE To relate fractional anisotropy (FA) changes associated with the semantic and logopenic variants of primary progressive aphasia (PPA) to measures of lexical retrieval. METHODS We collected neuropsychological testing, volumetric magnetic resonance imaging, and diffusion-weighted imaging on semantic variant PPA (svPPA) (n = 11) and logopenic variant PPA (lvPPA) (n = 13) patients diagn...
متن کاملTreatment for Lexical Retrieval in Primary Progressive Aphasia
: http://si p://pubs.as In recent years there has been an increase in research describing the behavioral characteristics and underlying pathology of primary progressive aphasia (PPA). One of the earliest and most prominent features of PPA, particularly for the logopenic and semantic variants, is anomia, and this is often the symptom that prompts individuals with PPA to seek treatment. However, ...
متن کاملNeural Correlates of Verbal Episodic Memory and Lexical Retrieval in Logopenic Variant Primary Progressive Aphasia
Objective: Logopenic variant primary progressive aphasia (lvPPA) is commonly associated with Alzheimer's disease (AD) pathology. But lvPPA patients display different cognitive and anatomical profile from the common clinical AD patients, whose verbal episodic memory is primarily affected. Reports of verbal episodic memory difficulty in lvPPA are inconsistent, and we hypothesized that their lexic...
متن کاملEmotion detection deficits and changes in personality traits linked to loss of white matter integrity in primary progressive aphasia
Non-cognitive features including personality changes are increasingly recognized in the three PPA variants (semantic-svPPA, non fluent-nfvPPA, and logopenic-lvPPA). However, differences in emotion processing among the PPA variants and its association with white matter tracts are unknown. We compared emotion detection across the three PPA variants and healthy controls (HC), and related them to w...
متن کاملGrammatical comprehension deficits in non-fluent/agrammatic primary progressive aphasia.
IMPORTANCE Grammatical comprehension difficulty is an essential supporting feature of the non-fluent/agrammatic variant of primary progressive aphasia (naPPA), but well-controlled clinical measures of grammatical comprehension are unavailable. OBJECTIVE To develop a measure of grammatical comprehension and examine this comparatively in PPA variants and behavioural-variant frontotemporal degen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2013
ISSN: 1664-2295
DOI: 10.3389/fneur.2013.00212